Previous work has reported that HGF/c-Met activation can confer hair cell protection from aminoglycoside damage, consistent with our results (Monahan and Samulski, Attenuation of aminoglycoside-induced hair cell death can result from two mechanistic categories: blockage of aminogly-coside uptake by hair cells or modulation of intracellular signaling pathways
In this context, the concept of molecular mimicry emerges as an innovative strategy: it is based on the design or use of biomolecules capable of imitating natural regulatory functions, such as certain peptides or lipids that mimic growth, antioxidant, or tissue repair signals
It is believed to promote angiogenesis (the formation of new blood vessels) and the regeneration of damaged tissues, speeding up the healing process for various injuries and improving overall tissue health
, The effectiveness of intradiscal biologic treatments for discogenic low back pain: a systematic review, Spine J
Place the vial upright in the refrigerator, ideally in the back where temperature is most stable
